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تمایز نوری بین بافت سالم و نا‌سالم با‌‌روش پراکندگی نور‌عبوری‌‌ و‌‌‌‌‌‌‌‌‌‌‌ تحلیل تابع هنیی-گرینشتاین

نویسندگان

زینب نبوی زاده
سلمان مهاجرمازندرانی

دانشکده فیزیک

https://doi.org/10.61882/jmrph.9.2.49
چکیده
امروزه سرطان به عنوان دومین عامل اصلی مرگ و میر در جهان شناخته می‌شود، بنابراین تشخیص زودهنگام آن اهمیت دارد. توده بدن به دو دسته کلی خوش‌خیم و بدخیم تقسیم می‌شود. تشخیص بین این دو نوع مهم‌ترین چالش برای پزشکان است. دستورالعمل‌های بالینی برای تشخیص سرطان محدودیت‌های متعددی دارند، مانند نیاز به متخصصان با تجربه، هزینه و زمان‌بر بودن. بنابراین، نیاز به استفاده از روش‌های کم‌هزینه و سریع احساس می‌شود. در این مطالعه، نمونه‌های خوش‌خیم-بدخیم دهانی و سالم-بیمار پوستی توسط میکروتوم برش داده شده و سپس روی لام‌ها ثابت شدند. با استفاده از روش پراکندگی نوری و محاسبه ضریب ناهمسانگردی (g) و پهنای‌تابع برازش هنی-گرینشتاین، تفاوت بین نمونه‌های خوش و بدخیم، سالم و بیمار پوستی تعیین می‌شود و تمایز بین آنها امکان‌پذیر است.

کلیدواژه‌ها

سرطان دهان
سرطان پوست
اسکلرودرمی
پراکندگی رو به جلو
تابع هنی-گرینشتاین

عنوان مقاله English

Optical Differentiation Between Normal And Abnormal Tissue By Henyey- Greenstein function analysis of Forward Scattering

نویسندگان English

Zeynab Nabavizadeh
Salman Mohajer Mazandarani
Physics Dep.
چکیده English

Nowadays cancer is known as the second leading cause of death in the world, so early detection is important. Body mass is divided into two general categories benign and malignant types; distinguishing between these types is the most important challenge for doctors. Clinical guidelines for cancer diagnosis have several limitations, such as the need for experienced specialists, cost, and time-consuming, so the need to use low-cost and fast methods is felt. In this study, benign, malignant and health, diseased samples were cut by microtome and then fixed on slides; by using the optical scattering method and calculation of anisotropy( g ) and the width of the H-G fitting function, the difference between benign and malignant samples is determined and differentiating between them is possible

کلیدواژه‌ها English

oral cancer
skin cancer
scleroderma
forward scattering
Henyey- Greenstein function
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